Subtitle
A retrospective study of adjuvant proton radiotherapy for breast cancer after lumpectomy: a comparison of conventional-dose and hypofractionated dose.
Fifty patients were treated with PT using two different regimens following lumpectomy. 14 patients received IMPT to a total dose of 50 Gy in 25 fractions, followed by a 10 Gy 4 fractionated boost to the lumpectomy cavity, while 36 received 40.05 Gy in 15 fractions and SIB 48 Gy to the lumpectomy cavity. Late toxicity occurred in three patients presented grade 1 pneumonitis; one patient graded 2 pneumonitis and two patients rib fracture in hypofractionated group, whereas no patient in the conventional group developed these late toxicities.