Subtitle
Side Effects of Proton Beam Radiotherapy Treatment on Iris Melanoma.
Subtitle
Side Effects of Proton Beam Radiotherapy Treatment on Iris Melanoma.
Proto therapy Time
September 2023
Executive summary
This study demonstrated PBR a successful treatment option with a high tumor control rate and low complication profile. 149 eyes of 149 patients were treated with whole PBR (wPBR: n = 51) or segmental PBR (sPBR: n = 98). Tumor recurrence developed in 3 patients (wPBR: 1/51; sPBR: 2/98). Severe side effects such as limbal stem cell failure were found only in the wPBR group (4/51; 7.8%). Secondary glaucoma developed in 31.4% of the wPBR group (16/51) compared with 1.0% in the sPBR group (1/98; P < 0.001).
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