Subtitle
Phase II Study of Proton Beam Radiation Therapy for Patients With Breast Cancer Requiring Regional Nodal Irradiation.
Subtitle
Phase II Study of Proton Beam Radiation Therapy for Patients With Breast Cancer Requiring Regional Nodal Irradiation.
Proto therapy Time
August 2019
Executive summary
This study evaluated 70 patients among who 63 patients (91%) had left-sided breast cancer, two had bilateral breast cancer, and five had right-sided breast cancer; 65 (94%) had stage II to III breast cancer; 68 (99%) received systemic chemotherapy; 50 (72%) underwent immediate reconstruction.
With the median follow-up of 55 months, the study reported that among 62 surviving patients, the 5-year rates for locoregional failure and overall survival were 1.5% and 91%. One patient developed grade 2 RP, and none developed grade 3 RP. No grade 4 toxicities occurred. The authors concluded that PBT for breast cancer has low toxicity rates and similar rates of disease control compared with historical data of conventional RT.
Key content topics
Top cancer treatments
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