Subtitle
A Comparative Analysis of Photon versus Proton Beam Therapy in Neoadjuvant Concurrent Chemoradiotherapy for Intrathoracic Squamous Cell Carcinoma of the Esophagus at a Single Institute.
Subtitle
A Comparative Analysis of Photon versus Proton Beam Therapy in Neoadjuvant Concurrent Chemoradiotherapy for Intrathoracic Squamous Cell Carcinoma of the Esophagus at a Single Institute.
Proto therapy Time
April 2022
Executive summary
This study compared the results of 31 patients with locally advanced esophageal cancer treated with neoadjuvant chemoradiotherapy to a median total dose 41.4 Gy using either proton (n = 15) or photon (n = 16). With a median follow-up of 17 months, this study reported no significant differences between the two groups in 2-year OS (67.8% vs. 68.6%, p = 0.867) or 2-year DFS (33.3% vs. 34.5%, p = 0.749). The lungs and heart received significantly less dose in the proton group, however there was no significant differences in short-term postoperative outcomes or lymphocyte count.
Key content topics
Top cancer treatments
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