Subtitle
Impact of lymphopenia on the clinical outcomes of esophageal cancer patients
Subtitle
Impact of lymphopenia on the clinical outcomes of esophageal cancer patients
Proto therapy Time
October 2021
Executive summary
A study by the Tsukuba group, Japan. This study retrospectively reviewed 69 patients with esophageal cancer treated with XRT (n=15) and PBT (n= 54) and concurrent chemotherapy. The study found that the absolute lymphocyte counts (ALC) were significantly higher in PBT group than the XRT group, and a similar trend was observed in the neutrophil-to-lymphocyte ratio (NLR). Dose-volume analysis revealed significant correlations between the volume of the thoracic bones irradiated by 5-50 Gy and the minimum ALCs and maximum NLR. This study suggested that PBT prevented the development of lymphopenia by reducing the irradiated volume of the thoracic bone.
Key content topics
Top cancer treatments
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