Proton Therapy Publication Proton Therapy Publication
Menu

Meta-analysis of the incidence and patterns of second neoplasms (SNs) after photon craniospinal irradiation (CSI) in children with medulloblastoma (MB).

April 2018
Executive summary

This meta-analysis reported that the 10-year cumulative incidence was 6.1% for all SNs, including 3.1% for SBNs (benign) and 3.7% for SMNs (malignant), with a majority in areas of exit RT dose.

Studies are needed to determine whether the use of proton therapy, which has no exit RT dose, is associated with a lower incidence of SNs.

Top cancer treatments
Pediatric
Brain and CNS

Related contents

Proton Therapy Publication
November 2024
Systematic review and meta-analysis of photon radiotherapy versus proton beam therapy for pediatric intracranial ependymoma: TRP-ependymoma 2024
en
Link to the fully detailed content
Proton Therapy Publication
December 2024
Evaluating the safety and efficacy of proton radiotherapy for intracranial pediatric ependymomas: A single-arm meta-analysis.
en
Link to the fully detailed content
Proton Therapy Publication
December 2024
Osteoradionecrosis in Pediatric Patients Treated with Proton Therapy for Head and Neck Malignancies.
en
Link to the fully detailed content
Proton Therapy Publication
September 2024
Outcomes of proton therapy to infradiaphragmatic sites in pediatric patients with Hodgkin lymphoma.
en
Link to the fully detailed content
Proton Therapy Publication
June 2024
Late-onset lymphopenia during radiation is associated with an increased risk of tumor recurrence in newly diagnosed pediatric medulloblastoma.
en
Link to the fully detailed content