Subtitle
Analysis of Gastrointestinal Toxicity in Patients Receiving Proton Beam Therapy for Prostate Cancer: A Single-Institution Experience.
A study by the Seattle group. 192 prostate cancer patients were treated with PBT. With the median follow-up of 1.7 years, most of the observed GI toxicity (>90%) was in the form of rectal bleeding (RB). GR2+ GI toxicity and RB actuarial rates specifically at 2 years were 21.3% and 20.4%, respectively. GR3 toxicity was rare, with only 1 observed RB event. No GR4/5 toxicity was seen.
High EPIC bowel domain quality of life was maintained in the 2 years after treatment.