Subtitle
Acute and long-term toxicity of whole pelvis proton radiation therapy for definitive or adjuvant management of gynecologic cancers.
This study reported outcomes of 23 patients with gynecologic malignancies treated with PBSPRT. 12 (52.2%) patients had uterine cancer, 10 (43.5%) cervical, and 1 (4.3%) vaginal. Median follow up was 4.8 years. 5-year actuarial LC was 95.2%, regional control 90.9%, distant control 74.7% and OS 91.3%. 2 patients (8.7%) had acute G2 GU toxicity, 6 (26.1%) acute GI G2-3 toxicity, and 17 (73.9%) acute G2-4 hematologic toxicity. 3 (13.0%) patients had late G2 GU toxicity, 1 (4.3%) late G2 GI toxicity, 2 (8.7%) late G2-3 hematologic toxicity.