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Proton beam therapy for clival chordoma: Optimising rare cancer treatments in Australia.

06/05/2024
/ Publications
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Quality assurance

This review evaluated clinical evidence of surgery, photon-based radiotherapy and proton therapy for clival chordoma. The authors stated that contemporaneous...

FLASH Radiotherapy: What Can FLASH's Ultra High Dose Rate Offer to the Treatment of Patients With Sarcoma?

06/05/2024
/ Publications
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FLASH Therapy
Dosimetry
Toxicity

A review article by the Upenn group summarized the preclinical and clinical evidence for the FLASH effect and discussed the potential clinical significance for...

Vision loss following high-dose proton-based radiotherapy for skull-base chordoma and chondrosarcoma

14/05/2021
/ Publications
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Dosimetry

This study included148 chordoma and chondrosarcoma patients and 283 individual eyes with functional vision at baseline who received a minimum 30GyRBE to 0.1cm3...

Particle Radiotherapy for Skull Base Chondrosarcoma: A Clinical Series from Italian National Center for Oncological Hadrontherapy.

14/09/2021
/ Publications
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Toxicity

This study reported outcomes of 48 patients with skull base chondrosarcoma who underwent particle therapy (67% PT, 33% CIRT). With a median follow-up of 38...

Definitive high-dose, proton-based radiation for unresected mobile spine and sacral chordomas.

14/06/2022
/ Publications
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Survival
Dosimetry

Sixty-seven patients with unresected spinal chordomas treated with PBT were evaluated. With a median follow-up of 56.2 months, 5- and 8-year OS were 83.5 % and...

Proton or Carbon Ion Therapy for Skull Base Chordoma: Rationale and First Analysis of a Mono-Institutional Experience.

14/03/2023
/ Publications
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Toxicity

This study reported clinical outcomes of 44 patients treated with proton (89%) or carbon ion therapy (11%). At a median follow-up of 34.3 months, 2-, and 3-year...

The role of combined ion-beam radiotherapy (CIBRT) with protons and carbon ions in a multimodal treatment strategy of inoperable osteosarcoma.

16/06/2021
/ Publications
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Toxicity

This study reported the outcomes of 20 patients with primary (N=18), metastatic (N=3), or recurrent (N=2) inoperable pelvic (70%) or craniofacial (30%)...

Proton Therapy for Primary Bone Malignancy of the Pelvic and Lumbar Region - Data From the Prospective Registries ProReg and KiProReg.

16/02/2022
/ Publications
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Toxicity

Eighty-one patients with primary bone malignancy, including Ewing’s sarcoma (58%), chondrosarcoma (7.4%), chordoma (24.7%), osteosarcoma (7.4%), and...