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Top cancer treatments

Clinical IMPT for Hodgkin lymphoma: which patients benefit the most?

01/01/2019
/ Publications
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Pencil Beam Scanning - PBS

21 HL patients treated with deep inspiration breath-hold pencil-beam scanning (PBS) PT. Normal tissue radiation doses were calculated and compared to doses from...

Proton theraphy for adults with mediastinal lymphomas: The international lymphoma radiation oncology group (ILROG) guidelines.

08/08/2018
/ Publications

Radiation treatment techniques that increase the excess radiation dose to organs at risk (OARs) puts patients at risk of increased side effects, especially late...

Evidence-based Review on the Use of PT in Lymphoma from the PTCOG Lymphoma Subcommittee.

05/09/2017
/ Publications

In an effort to draw attention to the use of proton therapy in lymphoma, and as a resource for future consideration of proton therapy coverage for lymphoma by...

Proton Therapy For Lymphomas: Current State Of The Art

07/10/2019
/ Publications
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Pencil Beam Scanning - PBS

A review of latest development on lymphomas management with proton therapy, including details of proton physic properties, delivery techniques of passive...

2-year relapse-free survival of 85% with no grade 3 toxicity

30/08/2016
/ Publications
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Toxicity

A registry study of collective proton centres reported a 2-year relapse-free survival of 85% with no grade 3 toxicity occurred. Hodgkin lymphoma young survivors...

Systematic Review for Deep Inspiration Breath Hold in Proton Therapy for Mediastinal Lymphoma: A PTCOG Lymphoma Subcommittee Report and Recommendations.

15/11/2022
/ Publications
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IMPT
IMRT

Published in the Green Journal, the PTCOG lymphoma subcommittee conducted a systematic review on available dosimetric studies comparing IMPT free breathing (FB)...

Proton and Carbon Ion Radiotherapy Decreased Severe Lymphopenia by Reducing Thoracic Vertebra and Aortic Dose in Non-small Cell Lung Cancer versus Intensity Modulated Radiotherapy.

16/01/2023
/ Publications

Published in the Red Journal, this study reported lymphopenia differences between IMRT and proton/carbon ion (PCIRT) for NSCLC. With data of 343 patients, this...

Evidence for external beam radiotherapy in mediastinal Hodgkin and non-Hodgkin lymphoma - systematic review.

06/05/2024
/ Publications
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Survival
Proton Reirradiation

This review included 11 studies representing a total of 529 patients. The findings include 1) the OS for 2 years varied from 91% - 98% for 5 of the included...

A bibliometric analysis of cardiotoxicity in cancer radiotherapy.

06/05/2024
/ Publications
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Quality of life
Survival

Radiation induced heart disease (RIHD) significantly impacts the long-term survival and quality of life of cancer survivors as one of the most devastating...

Risk of Pneumonitis and Outcomes After Mediastinal Proton Therapy for Relapsed/Refractory lymphoma: A PTCOG and PCG Collaboration.

16/01/2021
/ Publications
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Toxicity

Symptomatic pneumonitis, a subacute toxicity, has an incidence of 17% to 24% (≥grade 2) even with IMRT. A total of 85 patients with r/r lymphoma (66% HL, 34%...