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Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group.

10/11/2020
/ Publications
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Hypofractionation

This study analyzed the data of 63 patients with liver tumors treated with PBT. Hypofractionated PBT resulted in excellent local control, sparing of the...

Proton beam radiotherapy vs. radiofrequency ablation for recurrent hepatocellular carcinoma: a randomized phase trial.

01/10/2020
/ Publications
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Toxicity

This randomized study compared PBT and radiofrequency ablation (RFA) for patients with recurrent/residual HCC. The local progression free survival values of PBT...

Radiation-Associated Lymphopenia and Outcomes of Patients with Unresectable HCC Treated with Radiotherapy.

04/03/2021
/ Publications

Lymphopenia caused by radiotherapy is associated with a poor prognosis. This study reviewed 143 HCC patients treated with photon (n=103 (72%)) and proton (n=40...

Abscopal Effect Followiing PBRT in a Patient With Inoperable Metastatic Retroperitoneal Sarcoma.

09/09/2019
/ Publications
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Immunotherapy

The first case report of an abscopal effect in a patient of retroperitoneal sarcomas (RPS) treated with proton therapy. A 67 year-old female with inoperable...

Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma (B/P-RMS).

07/08/2019
/ Publications
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Toxicity

This study reported outcomes of 19 patients of B/P-RMS treated with PBT. With a median follow-up of 66.2 months, 5-year overall survival (OS) and progression...

Optimizing neoadjuvant radiotherapy for resectable and borderline resectable pancreatic cancer using protons.

07/07/2019
/ Publications

Approximately 25% of patients diagnosed with pancreatic cancer present with non-metastatic resectable or borderline resectable disease. Preoperative...

Proton beam therapy versus stereotactic body radiotherapy for hepatocellular carcinoma: practice patterns, outcomes, and the effect of biologically effective dose escalation.

07/10/2019
/ Publications

With the National Cancer Database for T1-2N0 HCC patients receiving PBT or SBRT, a total of 71 patients received PBT and 918 patients received SBRT were...

A comparison of the outcomes between surgical resection and proton beam therapy for single primary hepatocellular carcinoma.

07/10/2019
/ Publications

There were 314 and 31 patients with single primary nodular HCC ≤ 100 mm without vessel invasion who underwent surgical resection (SR) and PBT were analyzed. The...

Protons versus Photons for Unresectable Hepatocellular Carcinoma: Liver Decompensation and Overall Survival.

07/01/2019
/ Publications

Published in the Red Journal, this single-institution retrospective study compared clinical outcomes of proton versus photon ablative radiation therapy in...

Extreme hypofractionated proton radiotherapy for prostate cancer using pencil beam scanning: Dosimetry, acute toxicity and preliminary results.

07/09/2019
/ Publications
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Hypofractionation
Pencil Beam Scanning - PBS

A study by the research group in Prague. Two hundred patients with early-stage prostate cancer were treated with IMPT on extreme hypofractionated schedule (36...