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Clinical Outcomes of Proton Beam Therapy for Unresectable Locally Advanced Pancreatic Cancer: A Single-Center Retrospective Study.

05/11/2024
/ Publications

This study from Japan reported PBT treatment results for 54 unresectable stage III pancreatic cancer. PBT was performed using the passive method, with a median...

Particle therapy in gastrointestinal cancer-a narrative review.

05/11/2024
/ Publications

This is a review on particle therapy for GI cancers including esophageal, pancreatic, liver and anorectal cancers. Key dosimetric and clinical data of proton...

Cost-utility analysis of proton beam therapy for locally advanced esophageal cancer in Japan.

05/11/2024
/ Publications

This is a health-economic study from Japan. Using Markov model with the two existing levels of fees for PBT in social insurance i.e. 2,735,000 Japanese yen (US...

Risk of radiation-induced second malignant neoplasms from photon and proton radiotherapy in paediatric abdominal neuroblastoma

08/07/2021
/ Publications
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Secondary cancer

This study compared the carcinogenic risk associated with 3D-CRT, IMAT and PBS-PT)in the treatment of pediatric abdominal neuroblastoma. The risk of radiation...

Trends and variations in utilization and costs of radiotherapy for prostate cancer: A SEER medicare analysis from 2007 through 2016

08/02/2021
/ Publications
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IMPT

Based on the SEER database, this study reported that for Medicare beneficiaries with a first-time diagnosis of prostate cancer, the utilization of IMRT, proton...

Cross-modality applicability of rectal normal tissue complication probability models from photon- to proton-based radiotherapy.

01/10/2019
/ Publications

This study aimed to assess the applicability of photon-based NTCP models to rectum morbidity outcomes following PT for prostate cancer patients. The data of...

Retrospective analysis of reduced energy switching and room switching times on throughput efficiency of a multi-room proton therapy center.

11/12/2019
/ Publications

A 4-room center treating ~90 patients/day, treating for ~7 years underwent a software upgrade which reduced room and energy switching times from ~30 to~20 sec...

Hypofractionated Proton Therapy in Early Prostate Cancer: Results of a Phase I/II Trial at Loma Linda University.

11/08/2019
/ Publications
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Hypofractionation

A cohort of 146 patients with low-risk prostate cancer were treated to 60 Gy (cobalt Gy equivalent) of proton therapy (20 fractions of 3.0 Gy per fraction) in 4...

Proton beam therapy for hepatocellular carcinoma associated with inferior vena cava tumor thrombus.

11/11/2019
/ Publications
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Toxicity

Hepatocellular carcinoma (HCC) with inferior vena cava tumor thrombus (IVCTT) is rare and regarded as an advanced disease stage with a poor prognosis. This...

Clinical Outcomes of Patients With Unresectable Cholangiocarcinoma Treated With Proton Beam Therapy.

11/11/2019
/ Publications
/
Toxicity
Survival
Chemotherapy

This study from Taiwan retrospectively examined 30 patients with unresectable CC who were treated with PBT to a total dose of 72.6 GyRBE. The 1-year local...