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Clinical outcome after pencil beam scanning proton therapy and dysphagia/xerostomia NTCP calculations of proton and photon radiotherapy delivered to patients with cancer of the major salivary glands.

14/08/2023
/ Publications
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Survival
Toxicity

For the 26 patients with salivary gland tumor treated with PBSPT, at a median follow-up time of 46 months, 5 (19%), 2 (8%), 3 (12%) and 2 (8%) patients...

A systematic review and meta-analysis of osteoradionecrosis following proton therapy in patients with head and neck cancer.

14/01/2024
/ Publications
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Toxicity

Osteoradionecrosis (ORN), which is a serious complication and late toxicity of radiotherapy, has been reported in proton therapy. This meta-analysis included 17...

Proton versus photon radiation therapy: A clinical review.

16/03/2023
/ Publications
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Clinical Trial

This review summarized comparative clinical outcomes between proton and photon radiotherapy. 63 interventional comparative studies were presented in this...

Phase III randomized trial of intensity-modulated proton therapy (IMPT) versus intensity-modulated photon therapy (IMRT)

05/06/2024
/ Publications
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Clinical Trial

Patients (n=440) were randomized to undergo IMRT(n=219) or IMPT (n=221) at 21 institutions. The median age was 61 years and HPV/p16 was positive in 95%. IC was...

An Interview with Dr. Steven Frank

17/07/2024
/ Webinar
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Clinical Trial

Learn from Dr. Steven Frank as he discusses the results, challenges, and implications of the study "Phase III randomized trial of intensity-modulated proton...

The Radiosurgery Society Working Groups on GRID, LATTICE, Microbeam, and FLASH Radiotherapies: 2022 - 2023 Advancements Symposium and Subsequent Progress Made.

05/11/2024
/ Publications
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FLASH Therapy

This is a report of a symposium focusing on spatially fractionated radiotherapy (SFRT) including GRID, Lattice, Microbeam, as well as ultra-high dose rate...

Proton beam re-irradiation for gastrointestinal malignancies: a systematic review.

03/02/2020
/ Publications
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Reirradiation

A systematic review assessing for reports of proton-beam reirradiation for recurrent or second primary GI cancers. 7 included studies reported on proton-beam re...

Proton Reirradiation: Expert Recommendations for Reducing Toxicities and Offering New Chances of Cure in Patients With Challenging Recurrence Malignancies.

05/07/2020
/ Publications
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Toxicity
Reirradiation
IMPT

Published in Seminar Radiation Oncology, this review article evaluated clinical data up-to-date on proton reirradiation for local and regional recurrence. As...

FLASH Investigations Using Protons: Design of Delivery System, Preclinical Setup and Confirmation of FLASH Effect with Protons in AnimalSystems.

01/12/2020
/ Publications
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FLASH Therapy

Extremely high-dose-rate irradiation, referred to as FLASH, has been shown to be less damaging to normal tissues than the same dose administrated at...