Your results for

Filter by

Filter by
Results

Filter by

Content type
Key content topics
Key audience
Top cancer treatments

Conventional versus hypofractionated postmastectomy proton radiotherapy in the USA (MC1631): a randomised phase 2 trial.

23/11/2023
/ Publications

Published in the Lancet Oncology, this randomized phase 2 study by the Mayo group was set to compare conventional fractionated (50 Gy in 25 fractions of 2 Gy)...

Reconstructive complications and early toxicity in breast cancer patients treated with proton-based postmastectomy radiation therapy.

01/03/2024
/ Publications

This study compared acute toxicities and reconstructive complications in patients treated with proton-based (n = 11)and photon-based PMRT (n = 26). Grade 2 skin...

Future Perspectives of Proton Therapy in Minimizing the Toxicity of Breast Cancer Radiotherapy.

16/05/2021
/ Publications
/
Dosimetry
Reirradiation
Toxicity

A review article compared the clinical evidence including the parameters of the dose distribution in organs at risk, such as the heart, blood vessels, and lungs...

Proton Therapy for Partial Breast Irradiation: Rationale and Considerations.

16/04/2021
/ Publications
/
Reirradiation

A review specifically for PBT partial breast irradiation. This review found that tumor control with PT is excellent, and the toxicities associated with PT PBI...

A retrospective study of adjuvant proton radiotherapy for breast cancer after lumpectomy: a comparison of conventional-dose and hypofractionated dose.

16/03/2023
/ Publications
/
Dosimetry
Hypofractionation
Toxicity

Fifty patients were treated with PT using two different regimens following lumpectomy. 14 patients received IMPT to a total dose of 50 Gy in 25 fractions...

The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations.

16/02/2023
/ Publications
/
Toxicity

This review presented the rationale of using protons in the setting of locally advanced breast cancer, which is to mitigate treatment related toxicity...

Postmastectomy Intensity Modulated Proton Therapy: 5-Year Oncologic and Patient-Reported Outcomes.

16/11/2023
/ Publications
/
IMPT

127 patients received unilateral conventionally fractionated postmastectomy IMPT. Median follow-up was 4.1 years. Five-year LRC was 98.4% and OS was 87.9%...

Radiation-induced skin and heart toxicity in patients with breast cancer treated with adjuvant proton radiotherapy: a comparison with photon radiotherapy.

16/10/2023
/ Publications
/
Dosimetry
Toxicity

The active and inactive (pro-BNP and NT-proBNP) forms of BNP are classically used as biomarkers for diagnosing and monitoring acute and chronic heart failure...

Secondary Malignancy Risk Following Proton vs. X-ray Radiotherapy of Thymic Epithelial Tumors: A Comparative Modeling Study of Thoracic Organ-Specific Cancer Risk.

16/05/2022
/ Publications
/
IMRT
Secondary cancer

A modeling study demonstrated significant reduction in secondary malignancy (SM) with the use of PBS relative to both 3DCRT and IMRT for all independent...

The Role of Hypofractionation in Proton Therapy.

16/05/2022
/ Publications
/
Hypofractionation

A review examined the reported data of hypofractionation with PBT. Over 50 published manuscripts were included for analysis. The most common treatment regions...