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Late contrast enhancing brain lesions in proton treated low-grade glioma patients: clinical evidence for increased periventricular sensitivity and variable RBE.
Late radiation-induced contrast enhancing brain lesions (CEBL) on MR images after proton therapy of brain tumors have been observed to occur frequently in...
Proton Therapy Reduces the Likelihood of High-Grade Radiation-Induced Lymphopenia in Glioblastoma Patients: Phase II Randomized Study of Protons vs. Photons.
This is a randomized phase II trial compared the radiation-induced grade 3+ lymphopenia (G3+L), which was defined as an absolute lymphocyte count (ALC) nadir of...
Lower doses to hippocampi and other brain structures for skull-base meningiomas with IMPT compared to photon therapy.
This study systematically compared intensity modulated proton therapy (IMPT), non-coplanar volumetric modulated arc therapy (VMAT) and intensity modulated...
Normal tissue complication probability models in plan evaluation of children with brain tumors referred to proton therapy.
40 patients treated with PBT were selected for VMAT re-plan. The VMAT and delivered PT plans were compared by dose/volume metrics and NTCP models related to...
Are further studies needed to justify the use of proton therapy for paediatric cancers of the central nervous system?
A review article published in the Green Journal. Having analyzed the available data of PBT for paediatric cancers of the central nervous system (CNS), this...
Improved neuropsychological outcomes following proton therapy relative to x-ray therapy for pediatric brain tumor patients.
This study analyzed 125 children who received radiation (XRT or PRT) and had post-treatment neuropsychological evaluation including intelligence (IQ), attention...