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Hypofractionated Proton Therapy in Early Prostate Cancer: Results of a Phase I/II Trial at Loma Linda University.

11/08/2019
/ Publications
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Hypofractionation

A cohort of 146 patients with low-risk prostate cancer were treated to 60 Gy (cobalt Gy equivalent) of proton therapy (20 fractions of 3.0 Gy per fraction) in 4...

A population-based assessment of proton beam therapy utilization in California.

01/02/2020
/ Publications

Based on data from California Cancer Registry, this study reported that of the 2,499,510 people with a cancer diagnosis during the study period, 578,632 (23%)...

Proton beam radiotherapy for anal and rectal cancers.

03/02/2020
/ Publications
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Hypofractionation

A review article looked at the current status of PBT for anal and rectal cancers. PBT offers appealing potential to reduce toxicity, increase patient compliance...

Proton beam re-irradiation for gastrointestinal malignancies: a systematic review.

03/02/2020
/ Publications
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Reirradiation

A systematic review assessing for reports of proton-beam reirradiation for recurrent or second primary GI cancers. 7 included studies reported on proton-beam re...

Patient Reported Outcomes Following Proton Pencil Beam Scanning vs. Passive Scatter/Uniform Scanning for Localized Prostate Cancer: Secondary Analysis of PCG 001-09.

03/03/2020
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Pencil Beam Scanning - PBS

This study evaluated PROs with the Expanded Prostate Cancer Index Composite (EPIC) instrument for men with localized PC enrolled in PCG 001-09 (NCT01255748)...

Multivariate normal tissue complication probability models for rectal and bladder morbidity in prostate cancer patients treated with proton therapy

10/10/2020
/ Publications

The study included rectum and bladder DVHs, 2D rectal dose maps and relevant patient/treatment characteristics from 1151 prostate cancer cases treated with PT...

Comparative Analysis of 5-Year Clinical Outcomes and Patterns of Failure of Proton Beam Therapy (PBT) versus Intensity-Modulated Radiotherapy (IMRT) for Prostate Cancer in the Postoperative Setting

10/11/2020
/ Publications
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IMRT

This case-matched study analyzed 260 prostate cancer patients including 65 treated with PBT and 195 IMRT. At a median follow-up of 59 months, biochemical...

Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma (B/P-RMS).

07/08/2019
/ Publications
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Toxicity

This study reported outcomes of 19 patients of B/P-RMS treated with PBT. With a median follow-up of 66.2 months, 5-year overall survival (OS) and progression...

Extreme hypofractionated proton radiotherapy for prostate cancer using pencil beam scanning: Dosimetry, acute toxicity and preliminary results.

07/09/2019
/ Publications
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Hypofractionation
Pencil Beam Scanning - PBS

A study by the research group in Prague. Two hundred patients with early-stage prostate cancer were treated with IMPT on extreme hypofractionated schedule (36...

Comparative toxicity outcomes of PBT vs IMRT for prostate cancer in the postoperative setting.

07/09/2019
/ Publications
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Toxicity

A case-matched cohort analysis study compared acute and late genitourinary (GU) and gastrointestinal (GI) toxicity outcomes in patients with prostate cancer (PC...