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Phase II Study of Hypofractionated Proton Beam Therapy for Hepatocellular Carcinoma.

28/04/2020
/ Publications
/
Hypofractionation
Survival
Toxicity

Published by the NCC group in Korea, this study reported outcomes of 45 patients including 37 had recurrent and/or residual disease treated with PBT to a total...

Clinical results of active scanning proton therapy for primary liver tumors.

10/07/2020
/ Publications

This study reported clinical outcomes of 18 patients including 14 patients with hepatocellular carcinoma (HCC) and 3 patients with intrahepatic...

Proton beam radiotherapy for esophagus cancer: state of the art

10/11/2020
/ Publications
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Chemotherapy

The majority of esophageal cancer patients are diagnosed with locoregionally confined disease, which is often amenable to curative intent therapy...

The Potential Role of Intensity-Modulated Proton Therapy in Hepatic Carcinoma in Mitigating the Risk of Dose De-Escalation

10/12/2020
/ Publications
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VMAT
IMPT

A cohort of 30 patients was retrospectively selected as "at-risk" of dose de-escalation due to the proximity of the target volumes to dose-limiting healthy...

Efficacy and feasibility of proton beam radiotherapy using the simultaneous integrated boost technique for locally advanced pancreatic cancer

10/12/2020
/ Publications

A study by the NCC, Korea group analyzed 81 patients with locally advanced pancreatic cancer (LAPC), treated with PBT simultaneous integrated boost (SIB)...

Secondary Malignancy Risk Following Proton vs. X-ray Treatment of Mediastinal Malignant Lymphoma: A Comparative Modeling Study of Thoracic Organ-Specific Cancer Risk.

10/10/2020
/ Publications
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IMRT
Secondary cancer

This study estimated secondary cancer risks for 23 mediastinal lymphoma patients treated with PBT in comparison with helical photon IMRT re-plans. PBT was...

Hypofractionated proton beam radiotherapy in patients with unresectable liver tumors: multi-institutional prospective results from the Proton Collaborative Group.

10/11/2020
/ Publications
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Hypofractionation

This study analyzed the data of 63 patients with liver tumors treated with PBT. Hypofractionated PBT resulted in excellent local control, sparing of the...

Proton beam radiotherapy vs. radiofrequency ablation for recurrent hepatocellular carcinoma: a randomized phase trial.

01/10/2020
/ Publications
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Toxicity

This randomized study compared PBT and radiofrequency ablation (RFA) for patients with recurrent/residual HCC. The local progression free survival values of PBT...

Radiation-Associated Lymphopenia and Outcomes of Patients with Unresectable HCC Treated with Radiotherapy.

04/03/2021
/ Publications

Lymphopenia caused by radiotherapy is associated with a poor prognosis. This study reviewed 143 HCC patients treated with photon (n=103 (72%)) and proton (n=40...

Abscopal Effect Followiing PBRT in a Patient With Inoperable Metastatic Retroperitoneal Sarcoma.

09/09/2019
/ Publications
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Immunotherapy

The first case report of an abscopal effect in a patient of retroperitoneal sarcomas (RPS) treated with proton therapy. A 67 year-old female with inoperable...