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Top cancer treatments

Radiotherapy for Atypical Teratoid/Rhabdoid Tumor (ATRT) on the Pediatric Proton/Photon Consortium Registry (PPCR).

13/04/2023
/ Publications
/
Chemotherapy
Dosimetry

This study evaluated 68 patients with atypical teratoid/rhabdoid tumors (ATRT) treated with surgery (65% initial gross total resection or GTR), chemotherapy (60...

Gastrointestinal bleeding/ulcer among paediatric cancer patients after proton beam therapy.

13/06/2023
/ Publications
/
Reirradiation
Chemotherapy

This study analyzed 124 patients who underwent proton therapy with gastrointestinal tract involved in the irradiated field. The study reported gastrointestinal...

Neurocognitive outcomes in pediatric brain tumors after treatment with proton versus photon radiation: a systematic review and meta-analysis.

13/08/2023
/ Publications

Based on 10 studies including a total 630 patients, this review reported that proton therapy produced significantly higher scores for most analyzed...

Proton therapy for pediatric diencephalic tumors.

13/05/2023
/ Publications
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Toxicity

Tumors arise in the diencephalon including optic pathway/hypothalamic glioma, craniopharyngioma, germ cell tumors, and pituitary adenomas which tend to be low...

Proton Therapy Mediates Dose Reductions to Brain Structures Associated with Cognition in Children with Medulloblastoma.

13/11/2023
/ Publications
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Dosimetry

This study evaluated dosimetric and cognitive data from 75 patients with medulloblastoma treated with proton (n=36) and photon (n=39). Significant dose...

MGH’s 20 Years Treating with Protons and their Important Role in Pediatrics

29/09/2021
/ Podcast

September marks Childhood Cancer Awareness Month, so this episode will focus on pediatric cancer treatment and the many ways proton therapy can benefit children...

Young Adult Populations Face Yet Another Barrier to Care with Insurers: Limited Access to Proton Therapy.

16/08/2021
/ Publications
/
Toxicity
Secondary cancer

Young adult patients (n = 68/143, 48%) were significantly less likely to receive initial approval compared with pediatric patients (n = 139/141; 99%) (P < .001)...

Recent update of proton beam therapy for hepatocellular carcinoma: A systematic review and meta-analysis.

29/10/2024
/ Publications

This meta-analysis included 22 original studies involving 1858 HCC patients who received PBT to a total dose ranged from 55 GyE to 76 GyE. The median proportion...

Proton Beam Therapy for Treating Patients with Hepatocellular Carcinoma with Major Portal Vein Tumor Invasion: A Single Center Retrospective Study.

30/10/2024
/ Publications

This study from Japan reported favorable results of PBT in treatment of 116 patients with hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT...

Hypofractionated Radiotherapy-Related Lymphopenia Is Associated With Worse Survival in Unresectable Intrahepatic Cholangiocarcinoma.

30/10/2024
/ Publications

This multicenter study led by the MGH group retrospectively analyzed 96 patients with unresectable intrahepatic cholangiocarcinoma (ICC) treated with...