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Cross-modality applicability of rectal normal tissue complication probability models from photon- to proton-based radiotherapy.

01/10/2019
/ Publications

This study aimed to assess the applicability of photon-based NTCP models to rectum morbidity outcomes following PT for prostate cancer patients. The data of...

Retrospective analysis of reduced energy switching and room switching times on throughput efficiency of a multi-room proton therapy center.

11/12/2019
/ Publications

A 4-room center treating ~90 patients/day, treating for ~7 years underwent a software upgrade which reduced room and energy switching times from ~30 to~20 sec...

Hypofractionated Proton Therapy in Early Prostate Cancer: Results of a Phase I/II Trial at Loma Linda University.

11/08/2019
/ Publications
/
Hypofractionation

A cohort of 146 patients with low-risk prostate cancer were treated to 60 Gy (cobalt Gy equivalent) of proton therapy (20 fractions of 3.0 Gy per fraction) in 4...

Proton beam therapy for hepatocellular carcinoma associated with inferior vena cava tumor thrombus.

11/11/2019
/ Publications
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Toxicity

Hepatocellular carcinoma (HCC) with inferior vena cava tumor thrombus (IVCTT) is rare and regarded as an advanced disease stage with a poor prognosis. This...

Clinical Outcomes of Patients With Unresectable Cholangiocarcinoma Treated With Proton Beam Therapy.

11/11/2019
/ Publications
/
Toxicity
Survival
Chemotherapy

This study from Taiwan retrospectively examined 30 patients with unresectable CC who were treated with PBT to a total dose of 72.6 GyRBE. The 1-year local...

Hypofractionated Radiation Therapy for Unresectable/Locally Recurrent Intrahepatic Cholangiocarcinoma.

11/12/2019
/ Publications
/
Hypofractionation
Survival

This study by MGH retrospectively analyzed 66 patients with unresectable intrahepatic cholangiocarcinoma (ICC) who were treated with hypofractionated proton (32...

Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System.

01/02/2020
/ Publications
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FLASH Therapy

Published in the Red Journal by the UPenn group, this paper reported the effect of FLASH proton versus standard dose rate PRT on tumors and normal tissues in...

Clinical Limitations of Photon, Proton and Carbon Ion Therapy for Pancreatic Cancer.

01/01/2020
/ Publications
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Survival

This paper reviews the current status of photon and particle radiation therapy for pancreatic cancer in combination with systemic therapies and hypoxia...

Therapeutic results of proton beam therapy with concurrent chemotherapy for cT1 esophageal cancer and salvage endoscopic therapy for local recurrence.

01/01/2020
/ Publications
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Chemotherapy
Survival

This study from Japan reported the efficacy of 44 clinical T1 esophageal cancer patients treated with concurrent chemo-proton therapy (CCPT). 43 patients (98%)...

Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer.

03/03/2020
/ Publications
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IMRT
IMPT

Published in JCO (Journal of Clinical Oncology), this randomized trial compared total toxicity burden (TTB) and progression-free survival (PFS) between PBT and...