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Where are we with proton beam therapy for thoracic malignancies? Current status and future perspectives.

14/02/2021
/ Publications
/
Reirradiation

This review examines the evolving role of PBT in the treatment of thoracic malignancies and evaluates the data supporting its use. Clinical outcomes data of PBT...

Salvage proton beam therapy for locoregional recurrence of non-small cell lung cancer.

14/03/2021
/ Publications
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Toxicity

This study retrospectively reviewed 53 patients who received salvage PBT for locoregionally recurrent NSCLC. With a median follow-up time of 15.0 months, 26...

Proton beam radiotherapy for patients with early-stage and advanced lung cancer: a narrative review with contemporary clinical recommendations.

14/02/2021
/ Publications

A review article examined data available of proton radiation for early-stage, advanced-stage and recurrent NSCLC, as well as protons in post-operative...

Single Institution Experience of Proton and Photon-based Postoperative Radiation Therapy for Non-small-cell Lung Cancer.

14/09/2021
/ Publications
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IMRT
Toxicity

This study retrospectively evaluated 136 postoperative radiotherapy (PORT) patients (61 PBT, 75 IMRT). Median OS was 76 and 46 months for PBT and IMRT with...

Long-term outcomes of high-dose (74 GyE) proton beam therapy with concurrent chemotherapy for stage III nonsmall-cell lung cancer.

14/05/2021
/ Publications
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Dosimetry
Toxicity

This study reported outcomes of 45 patients with stage III NSCLC treated with PBT of 74 GyE and concurrent chemotherapy. With a median follow-up time of 42.1...

Clinical Outcomes of Pencil Beam Scanning Proton Therapy in Locally Advanced Non-Small Cell Lung Cancer: Propensity Score Analysis.

14/07/2021
/ Publications
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IMRT
Pencil Beam Scanning - PBS

For a cohort of 219 patients with stage III NSCLC who received definitive concurrent chemoradiotherapy, 25 patients (11.4%) underwent PBSPT and 194 patients (88...

Dosimetry, Efficacy, Safety, and Cost-Effectiveness of Proton Therapy for Non-Small Cell Lung Cancer.

14/09/2021
/ Publications
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Toxicity
IMRT

In the early-stage NSCLC setting, all of the studies had a small sample size and were single-arm without direct comparison. Proton therapy was promising for...

Prospective Study of Proton Therapy for Lung Cancer Patients with Poor Lung Function or Pulmonary Fibrosis.

15/05/2022
/ Publications
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Toxicity

This study reported results of PBT for 54 patients of inoperable stage I to III NSCLC with poor lung functions (defined as FEV1 ≤1.0 L, or FEV1≤50% predicted or...

Outcomes of proton therapy for non-small cell lung cancer in patients with interstitial pneumonia.

16/03/2022
/ Publications
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Toxicity

This study reported outcomes of 29 stage I to III NSCLC patients with interstitial pneumonia (IP) treated with PT. With a median follow up of 21.1 months, this...

Chemoradiation with Hypofractionated Proton Therapy in Stage II-III Non-Small Cell Lung Cancer: A Proton Collaborative Group Phase 1/2 Trial.

16/07/2022
/ Publications
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Toxicity
Chemotherapy

This study presented outcomes of a prospective multicenter trial with an early closure. Twenty-eight patients with stage II or III unresectable NSCLC were...