Acute radiation dermatitis among patients with nasopharyngeal carcinoma treated with proton beam therapy: Prognostic factors and treatment outcomes.
29/02/2024
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Publications
This study reported incidence of acute radiation dermatitis (ARD) of 57 NPC patients treated with PBT. The maximum ARD grade was 1, 2, and 3 in 26 (45.6%), 24...
Evaluation of Proton Therapy Reirradiation for Patients With Recurrent Head and Neck Squamous Cell Carcinoma.
01/03/2024
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Publications
This study analyzed 242 patients treated with PT-ReRT. Median follow-up was 12.0 months for all patients and 24.5 months for living patients. Median PT-ReRT...
Comparing the oncologic outcomes of proton therapy and intensity-modulated radiation therapy for head and neck squamous cell carcinoma.
08/04/2024
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Publications
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IMRT
IMPT
To compare the oncologic outcomes between proton therapy and intensity-modulated radiation therapy (IMRT) for head and neck squamous cell carcinoma (HNSCC)...
Longitudinal Assessment of Quality of Life in Nasopharyngeal Cancer Patients Treated with Intensity-Modulated Proton Therapy and Volumetric Modulated Arc Therapy at Different Time Points.
06/05/2024
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Publications
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IMPT
Quality of life
VMAT
This is a longitudinal assessment of QoL on 287 NPC patients treated with IMPT (n=41) and VMAT (n=246). Both groups exhibited improved scores of global QoL...
Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer.
06/05/2024
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Publications
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FLASH Therapy
Reirradiation
Toxicity
Survival
Published by the Upenn group, this study reported reduced xerostomia with FLASH proton compared to standard proton therapy in mice. The head and neck area of...
Outcomes and prognostic factors of major salivary gland tumors treated with proton beam radiation therapy
14/04/2021
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Publications
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Survival
This study reported clinical outcomes of 68 patients with major salivary gland tumors including the parotid gland (75.0%) and adenoid cystic carcinoma (22.1%)...
Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Nasopharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy.
14/06/2021
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Publications
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Toxicity
Survival
IMPT
Seventy-seven patients with nonmetastatic NPC received IMPT (n=28) or IMRT(n=49). With a median follow-up time of 30.3 months, IMPT was associated with lower...
Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy.
14/06/2021
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Publications
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IMPT
IMRT
Toxicity
This review suggested that IMPT could de-intensifies treatment through dose de-escalation to normal tissues without compromising dose to the primary tumor and...
A comparison of acute toxicities and patient-reported outcomes between intensity-modulated proton therapy and volumetric-modulated arc therapy after ipsilateral radiation for head and neck cancers.
14/02/2022
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Publications
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IMPT
VMAT
Toxicity
ARC therapy
A cohort of tonsil and salivary gland cancer patients who received ipsilateral curative-intent radiotherapy delivered by IMPT or VMAT were reviewed. This study...
Proton Therapy for Squamous Cell Carcinoma of the Head and Neck: Early Clinical Experience and Current Challenges.
14/05/2022
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Publications
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IMRT
Reirradiation
A significant reduction of toxicities, such as xerostomia, dysgeusia and feeding tube placement has been reported in studies of definitive PT for NPSCC...
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