Vision loss following high-dose proton-based radiotherapy for skull-base chordoma and chondrosarcoma
14/05/2021
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Publications
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Dosimetry
This study included148 chordoma and chondrosarcoma patients and 283 individual eyes with functional vision at baseline who received a minimum 30GyRBE to 0.1cm3...
Definitive high-dose, proton-based radiation for unresected mobile spine and sacral chordomas.
14/06/2022
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Publications
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Survival
Dosimetry
Sixty-seven patients with unresected spinal chordomas treated with PBT were evaluated. With a median follow-up of 56.2 months, 5- and 8-year OS were 83.5 % and...
Long-term outcomes of high-dose (74 GyE) proton beam therapy with concurrent chemotherapy for stage III nonsmall-cell lung cancer.
14/05/2021
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Publications
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Dosimetry
Toxicity
This study reported outcomes of 45 patients with stage III NSCLC treated with PBT of 74 GyE and concurrent chemotherapy. With a median follow-up time of 42.1...
Exposure of the heart in lung cancer radiation therapy: A systematic review of heart doses published during 2013 to 2020.
01/07/2022
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Publications
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Dosimetry
IMRT
Motion Management
Data of 140 dosimetry studies was analyzed. In the 105 non-SABR studies, the average MHD was similar between IMRT and 3DCRT (10.9 Gy versus 10.6 Gy) and lower...
ASTRO Radiation Therapy Summary of the ASCO Guideline on Management of Stage III Non-Small Cell Lung Cancer.
16/06/2023
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Publications
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Dosimetry
Based on the ‘Management of Stage III Non-Small-Cell Lung Cancer: ASCO Guideline’, this summary document makes recommendations directly related to RT for the...
Future Perspectives of Proton Therapy in Minimizing the Toxicity of Breast Cancer Radiotherapy.
16/05/2021
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Publications
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Dosimetry
Reirradiation
Toxicity
A review article compared the clinical evidence including the parameters of the dose distribution in organs at risk, such as the heart, blood vessels, and lungs...
A retrospective study of adjuvant proton radiotherapy for breast cancer after lumpectomy: a comparison of conventional-dose and hypofractionated dose.
16/03/2023
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Publications
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Dosimetry
Hypofractionation
Toxicity
Fifty patients were treated with PT using two different regimens following lumpectomy. 14 patients received IMPT to a total dose of 50 Gy in 25 fractions...
Radiation-induced skin and heart toxicity in patients with breast cancer treated with adjuvant proton radiotherapy: a comparison with photon radiotherapy.
16/10/2023
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Publications
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Dosimetry
Toxicity
The active and inactive (pro-BNP and NT-proBNP) forms of BNP are classically used as biomarkers for diagnosing and monitoring acute and chronic heart failure...
A phase II trial of hypofractionated high-dose proton beam therapy for unresectable liver metastases.
16/11/2022
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Publications
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Dosimetry
Toxicity
This study analyzed 46 patients with 49 liver metastases treated by PBT to a total dose of 60 GyRBE in 5 fractions (BED 132 GyE) or 70 GyRBE in 10 (BED 119 GyE)...
Proton Therapy in the Management of Pancreatic Cancer.
16/06/2022
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Publications
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Dosimetry
Reirradiation
Proton Reirradiation
Although proton treatment plans often showed advantages over photon plans in reducing dose to OARs, the clinical implications were yet to be proven. The key...
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