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Top cancer treatments

Ultrahigh dose-rate Flash irradiation increases the differential response between normal and tumor tissue in mice

07/07/2014
/ Publications
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FLASH Therapy

This is the foundation paper of the (re)discovery of FLASH at Curie. To determine the potential of ultrahigh dose-rate irradiation in radio-therapy, they...

Physicochemical model of reaction kinetics supports peroxyl radicalrecombination as the main determinant of the FLASH effect.

06/06/2020
/ Publications
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FLASH Therapy

A theoretical model that was developed collaboratively between Pr. Favaudon (Curie) and IBA in an attempt to explain the origin of the FLASH effect. This model...

3D range-modulator for scanned particle therapy-development, Monte Carlo simulations and experimental evaluation

23/07/2017
/ Publications
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FLASH Therapy

This article presents the concept of the Conformal Energy filter used by IBA in the Conformal FLASH. The aim of this approach, is to reduce the irradiation time...

Design and validation of a synchrotron proton beam line for FLASH radiotherapy preclinical research experiments.

12/12/2021
/ Publications
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Dosimetry
FLASH Therapy

This study by the MD Anderson group generated and validated the dosimetric accuracy of proton beams delivered by their synchrotron-based treatment delivery...

A universal range shifter and range compensator can enable proton pencil beam scanning single-energy Bragg peak FLASH-RT treatment using current commercially available proton systems.

07/01/2022
/ Publications
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FLASH Therapy

Published in the Red Journal, this study by the group from New York Proton Center (ProBeam) demonstrated FLASH dose rate based on current machine parameters...

FLASH Radiotherapy Using Single-Energy Proton PBS Transmission Beams for Hypofractionation Liver Cancer: Dose and Dose Rate Quantification.

07/12/2021
/ Publications
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FLASH Therapy
Hypofractionation

Another study by the group from New York Proton Center (ProBeam) assessed the feasibility of FLASH RT using single-energy transmission PBS plans of 4.5 Gy × 15...

Advanced pencil beam scanning Bragg peak FLASH-RT delivery technique can enhance lung cancer planning treatment outcomes compared to conventional multiple-energy proton PBS techniques.

13/09/2022
/ Publications
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Dosimetry
Pencil Beam Scanning - PBS
FLASH Therapy

Published in the Green Journal, this study by the group of New York Proton Center compared the dosimetric quality between an PBS Bragg peak FLASH and...

Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases: The FAST-01 Nonrandomized Trial.

15/11/2022
/ Publications
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FLASH Therapy

Published in JAMA, this is the results of the FAST-01 proton FLASH trial. This trial was set to test the clinical workflow feasibility, treatment related...

ConformalFLASH®: treat deeper, faster, and sharper with protons

08/12/2022
/ Webinar
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FLASH Therapy

FLASH can dramatically improve the clinical relevance of proton therapy for cancer patients worldwide. The development of FLASH irradiation is the next major...

ConformalFLASH® from model to delivery

31/05/2021
/ Webinar
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FLASH Therapy

What are the advantages of FLASH therapy? Where do we stand in FLASH therapy treatment planning? Watch this webinar to understand the latest developments in the...