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Proton Image-guided Radiation Assignment for Therapeutic Escalation via Selection of locally advanced head and neck cancer patients [PIRATES]: A Phase I safety and feasibility trial of MRI-guided adaptive particle radiotherapy.

06/11/2021
/ Publications
/
Hypofractionation
Toxicity
IMPT

This a study protocol that details a phase 1 trial investigating a new approach using image-guided proton therapy for dose escalation treatments for selected...

Proton therapy can be a safe and effective curative reirradiation strategy for head and neck cancer

30/09/2016
/ Publications
/
Toxicity
Reirradiation
Toxicity
Survival

Proton therapy can be a safe and effective curative reirradiation strategy for head and neck cancer, with acceptable rates of toxicity and durable disease...

2-year relapse-free survival of 85% with no grade 3 toxicity

30/08/2016
/ Publications
/
Toxicity

A registry study of collective proton centres reported a 2-year relapse-free survival of 85% with no grade 3 toxicity occurred. Hodgkin lymphoma young survivors...

Clinical outcomes and toxicities of proton radiotherapy for gastrointestinal neoplasms: a systematic review

30/08/2016
/ Publications
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Toxicity

A systematic review examined clinical outcomes and toxicities of proton therapy for gastrointestinal neoplasms. The findings include that proton therapy was...

Clinical Outcomes and Toxicity of Proton Radiotherapy for Breast Cancer

30/06/2016
/ Publications
/
Toxicity

A systematic review reported findings on clinical outcomes and toxicity of proton therapy for breast cancer.

Toxicity was comparable or improved to published...

Treating gastrointestinal malignancy with proton therapy

01/10/2016
/ White Paper
/
Toxicity
Dosimetry
Chemotherapy

The improved dosimetry with proton therapy enables greater sparing of normal tissues...

Treating head and neck cancer with proton therapy

30/12/2020
/ White Paper
/
Toxicity
IMRT
Dosimetry

Proton particles do not deposit exit dose, which allows proton therapy to spare normal tissues distal to the tumor target. This is particularly useful for...

Breast, The Value of Protons, Cardiotoxicity and RadComp

14/09/2022
/ Webinar
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Toxicity

During ISOP 2022, Shannon McDonald presented "Breast, The Value of Protons, Cardiotoxicity and RadComp".

Watch the webinar above.

Renal function in abdominal neuroblastoma patients undergoing proton radiotherapy.

12/01/2023
/ Publications
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Chemotherapy
Toxicity

This study examined the renal function of 30 children with abdominal neuroblastoma treated with PT. With a median follow-up 35 months, there was no patients...

Proton and photon radiotherapy in stage III NSCLC: Effects on hematological toxicity and adjuvant immune therapy.

28/03/2024
/ Publications
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IMPT
IMRT
Toxicity

This study reported the incidence of lymphopenia in 271 stage III NSCLC patients treated with IMPT (n=71) vs IMRT (n=200) and concurrent chemotherapy. The...