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Comparison of clinical outcomes between passive scattering versus pencil-beam scanning proton beam therapy for hepatocellular carcinoma.
A study by the Samsung group from Korea published in the Green Journal. A total of 103 patients treated with proton therapy including 70 in the PS group and 33...
Late contrast enhancing brain lesions in proton treated low-grade glioma patients: clinical evidence for increased periventricular sensitivity and variable RBE.
Late radiation-induced contrast enhancing brain lesions (CEBL) on MR images after proton therapy of brain tumors have been observed to occur frequently in...
Comparative analysis of acute toxicities and patient reported outcomes between intensity-modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT) for the treatment of oropharyngeal cancer.
This study compared 46 IMPT and 259 VMAT patients acute toxicities and reported that IMPT was associated with lower PEG-tube placement (p = 0.001) and less...
Patient Reported Outcomes Following Proton Pencil Beam Scanning vs. Passive Scatter/Uniform Scanning for Localized Prostate Cancer: Secondary Analysis of PCG 001-09.
This study evaluated PROs with the Expanded Prostate Cancer Index Composite (EPIC) instrument for men with localized PC enrolled in PCG 001-09 (NCT01255748)...
Acute Toxicities After Proton Beam Therapy Following Breast-Conserving Surgery for Breast Cancer: Multi-institutional Prospective PCG Registry Analysis. This is the report of the prospective multi-institutional Proton Collaborative Group registry study.
82 patients received PBT and their adverse events (AEs) were recorded prospectively at each institution. Median follow-up was 8.1 months. Median dose was 50.4...
Perspectives on the model-based approach to proton therapy trials: A retrospective study of a lung cancer randomized trial.
Published in the Green Journal, this study was to assess whether a model-based approach applied retrospectively to a completed randomized controlled trial (RCT)...
Hypofractionated Proton Therapy With Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer: A Phase I Trial From the University of Florida and Proton Collaborative Group.
Published in the Red Journal, this study reported the safety data from the first multicenter phase I trial investigating the use of hypofractionated proton...