Toxicity and Clinical Results after Proton Therapy for Pediatric Medulloblastoma: A Multi-Centric Retrospective Study.
13/06/2022
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Publications
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Toxicity
Pencil Beam Scanning - PBS
This study reported toxicities of 43 children with medulloblastoma treated with PBS-PT. The most common (>30% of patients) acute toxicities were radiation...
Radiotherapy for Atypical Teratoid/Rhabdoid Tumor (ATRT) on the Pediatric Proton/Photon Consortium Registry (PPCR).
13/04/2023
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Publications
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Chemotherapy
Dosimetry
This study evaluated 68 patients with atypical teratoid/rhabdoid tumors (ATRT) treated with surgery (65% initial gross total resection or GTR), chemotherapy (60...
Gastrointestinal bleeding/ulcer among paediatric cancer patients after proton beam therapy.
13/06/2023
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Publications
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Reirradiation
Chemotherapy
This study analyzed 124 patients who underwent proton therapy with gastrointestinal tract involved in the irradiated field. The study reported gastrointestinal...
Neurocognitive outcomes in pediatric brain tumors after treatment with proton versus photon radiation: a systematic review and meta-analysis.
13/08/2023
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Publications
Based on 10 studies including a total 630 patients, this review reported that proton therapy produced significantly higher scores for most analyzed...
Proton therapy for pediatric diencephalic tumors.
13/05/2023
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Publications
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Toxicity
Tumors arise in the diencephalon including optic pathway/hypothalamic glioma, craniopharyngioma, germ cell tumors, and pituitary adenomas which tend to be low...
Proton Therapy Mediates Dose Reductions to Brain Structures Associated with Cognition in Children with Medulloblastoma.
13/11/2023
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Publications
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Dosimetry
This study evaluated dosimetric and cognitive data from 75 patients with medulloblastoma treated with proton (n=36) and photon (n=39). Significant dose...
Proton and Heavy Particle Intracranial Radiosurgery.
13/01/2021
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Publications
This review provides a comprehensive overview of clinical evidence in the use of particle therapy-based radiosurgery. The vast majority of available data are...
Clinical trial of proton craniospinal irradiation for leptomeningeal metastases.
13/01/2021
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Publications
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Proton Reirradiation
This study reported the outcomes of 24 patients with leptomeningeal metastases (LM) treated with proton craniospinal irradiation (CSI). With the median follow...
Radiation-induced brain injury in patients with meningioma treated with proton or photon therapy.
13/05/2021
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Publications
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Survival
77 patients (38 proton and 39 photon) were evaluated with a median follow-up time of 2.2 years. This study reported no significant differences in symptomatic...
Proton therapy for adult medulloblastoma: Acute toxicity and disease control outcomes.
13/07/2021
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Publications
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Toxicity
Survival
Twenty adults with medulloblastoma (≥ 22 years old) received postoperative proton CSI. This study reported no acute ≥ grade 3 gastrointestinal or hematologic...
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