Proton or Carbon Ion Therapy for Skull Base Chordoma: Rationale and First Analysis of a Mono-Institutional Experience.
14/03/2023
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Publications
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Toxicity
This study reported clinical outcomes of 44 patients treated with proton (89%) or carbon ion therapy (11%). At a median follow-up of 34.3 months, 2-, and 3-year...
The role of combined ion-beam radiotherapy (CIBRT) with protons and carbon ions in a multimodal treatment strategy of inoperable osteosarcoma.
16/06/2021
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Publications
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Toxicity
This study reported the outcomes of 20 patients with primary (N=18), metastatic (N=3), or recurrent (N=2) inoperable pelvic (70%) or craniofacial (30%)...
Proton Therapy for Primary Bone Malignancy of the Pelvic and Lumbar Region - Data From the Prospective Registries ProReg and KiProReg.
16/02/2022
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Publications
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Toxicity
Eighty-one patients with primary bone malignancy, including Ewing’s sarcoma (58%), chondrosarcoma (7.4%), chordoma (24.7%), osteosarcoma (7.4%), and...
Proton beam re-irradiation for gastrointestinal malignancies: a systematic review.
03/02/2020
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Publications
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Reirradiation
A systematic review assessing for reports of proton-beam reirradiation for recurrent or second primary GI cancers. 7 included studies reported on proton-beam re...
Proton Reirradiation: Expert Recommendations for Reducing Toxicities and Offering New Chances of Cure in Patients With Challenging Recurrence Malignancies.
05/07/2020
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Publications
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Toxicity
Reirradiation
IMPT
Published in Seminar Radiation Oncology, this review article evaluated clinical data up-to-date on proton reirradiation for local and regional recurrence. As...
FLASH Investigations Using Protons: Design of Delivery System, Preclinical Setup and Confirmation of FLASH Effect with Protons in AnimalSystems.
01/12/2020
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Publications
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FLASH Therapy
Extremely high-dose-rate irradiation, referred to as FLASH, has been shown to be less damaging to normal tissues than the same dose administrated at...
PBT reirradiation for breast cancer: Multi-institutional prospective PCG registry analysis.
07/07/2019
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Publications
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Reirradiation
This study analyzed 50 patients received PBT reRT for breast cancer in the prospective Proton Collaborative Group (PCG) registry. Median reRT dose was 55.1 Gy...
IMPT - The future of IMRT for head and neck cancer.
01/01/2019
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Publications
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IMRT
Dosimetry
Imaging System
Reirradiation
A review article looked at the development of RT advances. There is a growing awareness of the potential clinical benefits of proton therapy over IMRT in the...
Proton beam therapy for cancer in the era of precision medicine.
11/12/2018
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Publications
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Dosimetry
Reirradiation
A general review on PBT inlcuding dosimetric advantage, clinical data on PBT for ocular tumor, skull base, paraspinal tumors (chondrosarcoma and chordoma), and...
Systematic assessment of clinical outcomes and toxicities of proton radiotherapy for reirradiation.
06/09/2017
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Publications
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Reirradiation
Toxicity
This review assessed clinical outcomes and toxicity profiles by evaluating available evidence regarding PBT reRT. The authors posit that PBT may be the safest...
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