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Comparison of the Effectiveness of Radiotherapy with 3D-CRT, IMRT, VMAT and PT for Newly Diagnosed Glioblastoma: A Bayesian Network Meta-Analysis.

14/12/2023
/ Publications
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IMRT
VMAT

Based on six original studies including 816 glioblastoma multiforme patients, this comprehensive synthesis of data performed by a Bayesian network meta-analysis...

Vision loss following high-dose proton-based radiotherapy for skull-base chordoma and chondrosarcoma

14/05/2021
/ Publications
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Dosimetry

This study included148 chordoma and chondrosarcoma patients and 283 individual eyes with functional vision at baseline who received a minimum 30GyRBE to 0.1cm3...

Particle Radiotherapy for Skull Base Chondrosarcoma: A Clinical Series from Italian National Center for Oncological Hadrontherapy.

14/09/2021
/ Publications
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Toxicity

This study reported outcomes of 48 patients with skull base chondrosarcoma who underwent particle therapy (67% PT, 33% CIRT). With a median follow-up of 38...

Definitive high-dose, proton-based radiation for unresected mobile spine and sacral chordomas.

14/06/2022
/ Publications
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Survival
Dosimetry

Sixty-seven patients with unresected spinal chordomas treated with PBT were evaluated. With a median follow-up of 56.2 months, 5- and 8-year OS were 83.5 % and...

Proton or Carbon Ion Therapy for Skull Base Chordoma: Rationale and First Analysis of a Mono-Institutional Experience.

14/03/2023
/ Publications
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Toxicity

This study reported clinical outcomes of 44 patients treated with proton (89%) or carbon ion therapy (11%). At a median follow-up of 34.3 months, 2-, and 3-year...

Outcomes and prognostic factors of major salivary gland tumors treated with proton beam radiation therapy

14/04/2021
/ Publications
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Survival

This study reported clinical outcomes of 68 patients with major salivary gland tumors including the parotid gland (75.0%) and adenoid cystic carcinoma (22.1%)...

Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Nasopharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy.

14/06/2021
/ Publications
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Toxicity
Survival
IMPT

Seventy-seven patients with nonmetastatic NPC received IMPT (n=28) or IMRT(n=49). With a median follow-up time of 30.3 months, IMPT was associated with lower...

Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy.

14/06/2021
/ Publications
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IMPT
IMRT
Toxicity

This review suggested that IMPT could de-intensifies treatment through dose de-escalation to normal tissues without compromising dose to the primary tumor and...

A comparison of acute toxicities and patient-reported outcomes between intensity-modulated proton therapy and volumetric-modulated arc therapy after ipsilateral radiation for head and neck cancers.

14/02/2022
/ Publications
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IMPT
VMAT
Toxicity
ARC therapy

A cohort of tonsil and salivary gland cancer patients who received ipsilateral curative-intent radiotherapy delivered by IMPT or VMAT were reviewed. This study...

Proton Therapy for Squamous Cell Carcinoma of the Head and Neck: Early Clinical Experience and Current Challenges.

14/05/2022
/ Publications
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IMRT
Reirradiation

A significant reduction of toxicities, such as xerostomia, dysgeusia and feeding tube placement has been reported in studies of definitive PT for NPSCC...