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Top cancer treatments

Clinical practice vs state-of-the-art research and future visions- Report on the 4D treatment planning workshop for particle therapy

16/02/2021
/ Publications
/
ARC therapy
Dosimetry
Model-based approach

This is an overview of research advancements in motion-imaging and on research and clinical implementation of 4D particle therapy.

The main aspects regarding...

Spot-Scanning Proton Arc SPArcTherapy - the first robust and delivery-efficient spot-scanning proton arc therapy

08/08/2016
/ Publications
/
ARC therapy
IMPT

First publication on a variable energy proton Arc method: a robust and delivery-efficient spot-scanning proton arc therapy technique (aka SPArc). The aim was to...

4D robust optimization including uncertainties in time structures can reduce the interplay effect in proton pencil beam scanning radiation therapy

09/09/2018
/ Publications
/
Clinical Trial
Pencil Beam Scanning - PBS

Interplay effects in PB-PT, can be reduced by generating "time structures" that align to different time-points of the breathing cycle, delivering accurately the...

Effectiveness of different rescanning techniques for scanned proton RT in lung cancer patients

04/04/2018
/ Publications

Repainting: Repainting (aka rescanning) has the potential to reduce interplay effects. The spacing between rescans in breath-sampled (BS) techniques was set at...

Fattori Commissioning and QA for PBS PT optic tracking

07/07/2020
/ Publications
/
Pencil Beam Scanning - PBS
Commissioning
Quality assurance

The commissioning and quality assurance of a clinical protocol for respiratory gating in pencil beam scanning proton therapy for cancer patients with moving...

Emerging Therapies – New ways to reduce toxicity beyond Proton Therapy

16/12/2021
/ User Meeting
/
FLASH Therapy
Toxicity
Cone Beam CT - CBCT
  • Watch this user meeting on emerging therapies to reduce toxicity beyond Proton Therapy.
  •  
  • Dr. Kim, Dr. Prezado and Dr Mohiuddin explain three different...

Ultrahigh dose-rate Flash irradiation increases the differential response between normal and tumor tissue in mice

07/07/2014
/ Publications
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FLASH Therapy

This is the foundation paper of the (re)discovery of FLASH at Curie. To determine the potential of ultrahigh dose-rate irradiation in radio-therapy, they...

Does FLASH deplete oxygen-Experimental Evaluation for photons, protons and carbon ions

23/03/2021
/ Publications

Experimental results (in water) indicating that oxygen consumption during irradiation with x-rays, protons and carbon ions at varying doses (up to 340 Gy/sec)...

Design and commissioning of an image-guided small animal radiation platform and quality assurance protocol for integrated proton

23/07/2019
/ Publications
/
Commissioning

This article presents the FLASH results of UPenn. An image-guided small animal proton research system was developed to enable in vivo investigations of...

Physicochemical model of reaction kinetics supports peroxyl radicalrecombination as the main determinant of the FLASH effect.

06/06/2020
/ Publications
/
FLASH Therapy

A theoretical model that was developed collaboratively between Pr. Favaudon (Curie) and IBA in an attempt to explain the origin of the FLASH effect. This model...