Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer.
03/03/2020
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Publications
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IMRT
IMPT
Published in JCO (Journal of Clinical Oncology), this randomized trial compared total toxicity burden (TTB) and progression-free survival (PFS) between PBT and...
The emerging role of proton therapy for esophagus cancer.
03/02/2020
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Publications
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Survival
This review article discussed the emerging role of PBT for esophageal cancer, including rationale, treatment planning, early dosimetric and clinical comparisons...
Proton beam therapy for liver cancers.
03/02/2020
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Publications
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Dosimetry
Toxicity
A review article examined the latest utilization of PBT for hepatocellular carcinoma and cholangiocarcinoma, as well as liver metastasis. The dosimetric...
Proton beam radiotherapy for pancreas cancer.
03/02/2020
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Publications
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Hypofractionation
Chemotherapy
A review article examined up to date data of PBT for pancreatic cancer. For both resectable and unresectable pancreatic cancer, the clinical outcome data is...
Proton beam radiotherapy for anal and rectal cancers.
03/02/2020
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Publications
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Hypofractionation
A review article looked at the current status of PBT for anal and rectal cancers. PBT offers appealing potential to reduce toxicity, increase patient compliance...
Proton beam re-irradiation for gastrointestinal malignancies: a systematic review.
03/02/2020
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Publications
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Reirradiation
A systematic review assessing for reports of proton-beam reirradiation for recurrent or second primary GI cancers. 7 included studies reported on proton-beam re...
Comparison of clinical outcomes between passive scattering versus pencil-beam scanning proton beam therapy for hepatocellular carcinoma.
03/03/2020
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Publications
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Survival
A study by the Samsung group from Korea published in the Green Journal. A total of 103 patients treated with proton therapy including 70 in the PS group and 33...
Proton beam therapy utilization in adults with primary brain tumors in the United States.
03/03/2020
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Publications
Based on the National Cancer Database, a total of 1,296 patients received PBT from 2004 and 2015 for treatment of their primary brain tumor. High-grade glioma...
Late contrast enhancing brain lesions in proton treated low-grade glioma patients: clinical evidence for increased periventricular sensitivity and variable RBE.
03/03/2020
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Publications
Late radiation-induced contrast enhancing brain lesions (CEBL) on MR images after proton therapy of brain tumors have been observed to occur frequently in...
Comparative analysis of acute toxicities and patient reported outcomes between intensity-modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT) for the treatment of oropharyngeal cancer.
03/03/2020
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Publications
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IMPT
Chemotherapy
VMAT
This study compared 46 IMPT and 259 VMAT patients acute toxicities and reported that IMPT was associated with lower PEG-tube placement (p = 0.001) and less...
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