Published in the British Journal of Radiology by the Groningen group, this review paper examined the outcome reports of oropharyngeal cancer patients treated PBT patients. Oropharyngeal cancer has better survival than patients with squamous cell carcinoma of other head and neck subsites, especially when related to human papillomavirus.

The prevention of radiation-induced xerostomia and dysphagia and subsequent improvement of health-related quality of life can be obtained by applying proton therapy. Proton therapy results in lower dose levels in multiple organs at risk, which translates into reduced acute toxicity. The model-based approach for selecting patients for proton therapy in the Netherlands was discussed in this review.