Proton Therapy Publication Proton Therapy Publication
Menu

A physicochemical model of reaction kinetics supports peroxyl radicalrecombination as the main determinant of the FLASH effect.

June 2020
Check full study
Please connect to access this resource and get a more personalized Campus experience
Connect
Executive summary

A theoretical model that was developed collaboratively between Pr. Favaudon (Curie) and IBA in an attempt to explain the origin of the FLASH effect. This model predicts that contrary to common belief, the oxygen depletion might not necessarily be the underlying cause of the FLASH effect. Interestingly, this model also predicts that the FLASH effect may occur under normoxic conditions without a substantial depletion of the free O2 in the tissue.

 

Key content topics
FLASH Therapy

Related contents

Proton Therapy Publication
Proton therapy publication
October 2024
The Radiosurgery Society Working Groups on GRID, LATTICE, Microbeam, and FLASH Radiotherapies: 2022 - 2023 Advancements Symposium and Subsequent Progress Made.
Link to the fully detailed content
Proton Therapy Publication
March 2024
FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach.
en
Link to the fully detailed content
Proton Therapy Publication
April 2024
FLASH Radiotherapy: What Can FLASH's Ultra High Dose Rate Offer to the Treatment of Patients With Sarcoma?
en
Link to the fully detailed content
Proton Therapy Publication
April 2024
Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer.
en
Link to the fully detailed content