Subtitle
Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients.
Subtitle
Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients.
Proto therapy Time
June 2022
Executive summary
This study compared hematologic toxicity in 41 anal cancer patients treated with IMPT (n=14) or IMRT (n=27). This study found all pelvic bone marrow dose metrics lower and a significantly lower active bone marrow mean dose in patients receiving IMPT. However, there was no statistically significant difference in hematologic toxicity between the groups. Seventy percent of patients treated with IMRT had at least 1 grade ≥3 hematologic event compared with 86% in the IMPT group (P=0.48).
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